While lower-rely MBL hardly ever progresses to CLL, substantial-rely MBL progresses to CLL requiring therapy at a rate of 1% to 2% annually. Significant-rely MBL is distinguished from Rai 0 CLL based upon if the B-cell count is above or down below five × 109/L. Despite the fact that folks with the two higher-count MBL and CLL Rai phase 0 are at en